Volume 4 Supplement 2

Abstracts of the 16th International Charles Heidelberger Symposium on Cancer Research

Meeting abstracts

Edited by Ana M Urbano, A J Guiomar, Carlos F Oliveira, Isabel M Carreira and Maria C Alpoim

The 16th International Charles Heidelberger Symposium on Cancer Research thanks ACIMAGO, BPI, FCT, FLAD, Pfizer, Fundação Champalimaud, Alfagene, Reagente 5 and Câmara Municipal de Montemor o Velho who sponsor this Symposium.

16th International Charles Heidelberger Symposium on Cancer Research. Go to conference site.

Coimbra, Portugal26-28 September 2010

Concatenated PDF 4S2

Page 2 of 2

MDR modulation in colorectal adenocarcinoma cell lines: kinetic studies using ^99mTc-sestamibi

Authors: João Casalta-Lopes, A Margarida Abrantes, Joana Rio, Mafalda Laranjo, Bárbara Oliveiros, A Cristina Gonçalves, Ana B Sarmento-Ribeiro and M Filomena Botelho

Citation: BMC Proceedings 2010 4(Suppl 2):P22

Content type: Poster presentation Published on: 24 September 2010
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Phenotypic analysis of breast cell lines – triple negative cells vs expressing hormonal receptors

Authors: Mafalda Laranjo, Maria J Carvalho, Artur Paiva, A Margarida Abrantes, Isabel Torgal, Carlos F Oliveira and M Filomena Botelho

Citation: BMC Proceedings 2010 4(Suppl 2):P23

Content type: Poster presentation Published on: 24 September 2010
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16th International Charles Heidelberger Symposium on Cancer Research

Authors:

Citation: BMC Proceedings 2010 4(Suppl 2):P24

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A nonconjugated naphthalene derivative of meso-tetra-(3-hydroxy)-phenyl-porphyrin as a sensitizer for photodynamic therapy

Authors: Abílio JFN Sobral, Ana M Urbano, Pedro Silva, Sofia M Fonseca, Cláudia T Arranja and Hugh D Burrows

Citation: BMC Proceedings 2010 4(Suppl 2):P25

Content type: Poster presentation Published on: 24 September 2010
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Polyaromatic hydrocarbons accentuate malignant phenotype of the PC3 prostate cancer cell line

Authors: Mariana O Freitas, José Oliveira, Ana M Fernandes, Maria I Coutinho, Vera Alves, Anabela Mota-Pinto and Ana B Sarmento-Ribeiro

Citation: BMC Proceedings 2010 4(Suppl 2):P26

Content type: Poster presentation Published on: 24 September 2010
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MGBG–cisplatin combination chemotherapy against breast cancer

Authors: Raquel F Gonsalves and Maria PM Marques

Citation: BMC Proceedings 2010 4(Suppl 2):P27

Content type: Poster presentation Published on: 24 September 2010
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Melanoma skin cancer: could chromone derivatives be efficient chemopreventors?

Authors: Mafalda M Dias and Maria PM Marques

Citation: BMC Proceedings 2010 4(Suppl 2):P28

Content type: Poster presentation Published on: 24 September 2010
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Exosomes from human ovarian carcinoma SKOV3 cells are enriched in glycosylated proteins

Authors: Cristina Escrevente, Peter Altevogt and Júlia Costa

Citation: BMC Proceedings 2010 4(Suppl 2):P29

Content type: Poster presentation Published on: 24 September 2010
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Delocalized lipophilic cations as a new therapeutic approach in cancer

Authors: A Barbosa Ribeiro, A Luísa Ferreira, A Cristina Gonçalves, Sílvia Neves, A Maria Araújo, Filipa Carvalho, João Carvalho, Rui M Santos, Vera Alves, Teresa Silva, José M Nascimento-Costa and Ana B Sarmento-Ribeiro

Citation: BMC Proceedings 2010 4(Suppl 2):P30

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Cytotoxic effect induced by combination of polyamines metabolites and endocannabinoid, anandamide, on human cancer cells: a new anticancer strategy

Authors: Ana Batista-de-Carvalho, Giampiero Tempera, Nikenza Viceconte, Stefania Saccoccio, Eris Bidollari, Mariana Nalli, Enrico Morera, Giorgio Ortar and Enzo Agostinelli

Citation: BMC Proceedings 2010 4(Suppl 2):P31

Content type: Poster presentation Published on: 24 September 2010
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An in vitro tumor-fibroblast interaction model of human oral squamous cell carcinoma

Authors: Jozséf Dudás, Mario Bitsche, Volker Schartinger, Georg M Sprinzl and Herbert Riechelmann

Citation: BMC Proceedings 2010 4(Suppl 2):P32

Content type: Poster presentation Published on: 24 September 2010
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Physiologic parameters variation in ICR mice during a chemical induced liver carcinogenesis experiment

Authors: Ivo Conceição-Pereira, Nuno M Paula-Santos, Filipa O Pereira, Maria J Pires, Luis F Palomino, Aura A Colaço and Paula A Oliveira

Citation: BMC Proceedings 2010 4(Suppl 2):P33

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Role of VEGF signalling in the regulation of KDR expression in endothelial and tumoral microenvironment

Authors: Jacinta Serpa, Cheila Torre, Francisco Caiado and Sérgio Dias

Citation: BMC Proceedings 2010 4(Suppl 2):P34

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EP4-mediated prostanoid signalling promotes oral cancer progression

Authors: Karen Sapienza, Stewart Sale, Angela Hague, Ian R Hart, John F Marshall and Gareth J Thomas

Citation: BMC Proceedings 2010 4(Suppl 2):P35

Content type: Poster presentation Published on: 24 September 2010
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Role of notch pathway and HNF1 in cell death induced by HDACs inhibitors in ovarian cancer cell lines, serous and clear cells

Authors: Fernanda Silva, Jacinta Serpa, Germana Domingues, Gabriela Silva, António Almeida and Ana Félix

Citation: BMC Proceedings 2010 4(Suppl 2):P36

Content type: Poster presentation Published on: 24 September 2010
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TRAP1 and SORCIN cooperate in a survival pathway responsible for inducing drug-resistance in human colorectal carcinoma (CRC)

Authors: Matteo Landriscina, Francesca Maddalena, Gabriella Laudiero, Maria R Amoroso, Annamaria Piscazzi, Valentina Lombardi, Alberto Fersini and Franca Esposito

Citation: BMC Proceedings 2010 4(Suppl 2):P37

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Dll4 blockade interferes with the bone marrow vascular niche and perturbs hematopoietic recovery following myeloablation

Authors: Leonor Remédio, Tânia Carvalho and Sérgio Dias

Citation: BMC Proceedings 2010 4(Suppl 2):P38

Content type: Poster presentation Published on: 24 September 2010
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Short-chain sphingolipids for enhanced cellular uptake of liposome-encapsulated amphiphilic anti-cancer drugs

Authors: Lília RC Pedrosa, Albert van Hell, Wim van Blitterswijk, Ann LB Seynhaeve, Alexander MM Eggermont, Timo LM ten Hagen, Marcel Verheij and Gerben A Koning

Citation: BMC Proceedings 2010 4(Suppl 2):P39

Content type: Poster presentation Published on: 24 September 2010
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Osteosarcoma contains a subpopulation of cancer stem-like cells that are highly resistant to radiotherapy

Authors: Sara RM Neves, Aurio OG Lopes, Anália do Carmo, Antero J Abrunhosa, Paulo CPS Simões, Artur A Paiva, M Filomena Botelho and Célia MF Gomes

Citation: BMC Proceedings 2010 4(Suppl 2):P40

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Indentification of cancer stem-like cells in osteosarcoma and their implications in response to chemotherapy

Authors: Áurio O Lopes, Sara R Neves, Anália do Carmo, Artur A Paiva, Maria Botelho and Célia M Gomes

Citation: BMC Proceedings 2010 4(Suppl 2):P41

Content type: Poster presentation Published on: 24 September 2010
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Metabolic responses of A549 lung cells to cisplatin and radiation exposure studied by ¹H NMR spectroscopy

Authors: Ana F Ladeirinha, Inês D Lamego, Ana M Gil, Joana B Melo, Isabel M Carreira and Iola F Duarte

Citation: BMC Proceedings 2010 4(Suppl 2):P42

Content type: Poster presentation Published on: 24 September 2010
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In vivo pulmonary metastatic profile of breast cancer cell lines expressing hormonal receptors versus triple negative

Authors: M João Carvalho, A Margarida Abrantes, Mafalda Laranjo, Francisco Falcão, Silvério Cabrita, M Filomena Botelho, Carlos F de Oliveira and Isabel Torgal

Citation: BMC Proceedings 2010 4(Suppl 2):P43

Content type: Poster presentation Published on: 24 September 2010
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New targeted therapies in myelodysplastic syndrome: the role of farnesyltransferase and proteasome inhibitors

Authors: A Cristina Gonçalves, Ana Oliveira, Diana Moreira, Silvia Neves, Vera Alves, Teresa Silva, Luís Mesquita, Henriqueta Coimbra, Marília Dourado, José M Nascimento-Costa and Ana B SarmentoRibeiro

Citation: BMC Proceedings 2010 4(Suppl 2):P44

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Targeted gene silencing for cancer treatment

Authors: Lígia CG da Silva, José S Ramalho, M Conceição P de Lima, Sérgio Simões and João N Moreira

Citation: BMC Proceedings 2010 4(Suppl 2):P45

Content type: Poster presentation Published on: 24 September 2010
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Recombinant trail: a synergistic effect in myeloid leukemias

Authors: Filipa Carvalho, A Sofia Coelho, Cátia Domingues, João A Carvalho, André Ribeiro, Rui M Santos, A Cristina Gonçalves, Vera Alves, Teresa Silva, Marília Dourado, José M Nascimento-Costa and Ana B Sarmento-Ribeiro

Citation: BMC Proceedings 2010 4(Suppl 2):P46

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Co-expression of E- and P-cadherin in breast cancer: role as an invasion suppressor or as an invasion promoter?

Authors: Ana S Ribeiro, Laura C Carreto, André Albergaria, Bárbara Sousa, Sara Ricardo, Fernanda Milanezi, Raquel Seruca, Manuel A Santos, Fernando Schmitt and Joana Paredes

Citation: BMC Proceedings 2010 4(Suppl 2):P47

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Contribution of Thomsen-Friedenreich antigens to bladder cancer malignancy: Characterization of cell line models

Authors: Paulo F Severino, Mylène A Carrascal, Helena Gouveia, M Guadalupe Cabral, Manuela Correia, Nadia Malagolini, Mariella Chiricolo, Fabio Dall’Olio and Paula A Videira

Citation: BMC Proceedings 2010 4(Suppl 2):P48

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Antitumoral effect of farnesiltransferase and mtor inhibitors in hepatocellular carcinoma: in vitro studies

Authors: Ana M Araújo, Sílvia S Neves, Ana L Ferreira, Diogo Branco, Ana B Sarmento-Ribeiro and José M Nascimento-Costa

Citation: BMC Proceedings 2010 4(Suppl 2):P49

Content type: Poster presentation Published on: 24 September 2010
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Metalloproteinase inhibitors as a potential therapeutic approach in multiple myeloma: a preliminary study

Authors: A Sofia Pais, A Cristina Gonçalves, Catarina Geraldes, José M Nascimento-Costa and Ana B Sarmento-Ribeiro

Citation: BMC Proceedings 2010 4(Suppl 2):P50

Content type: Poster presentation Published on: 24 September 2010
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Novel antitumor DNA monoalkylating agents: Synthesis and biological evaluation

Authors: Ana F Brito, M Isabel Soares, Mafalda Laranjo, A Margarida Abrantes, José A Paixão, Ana M Beja, Manuela R Silva, Teresa P Melo and M Filomena Botelho

Citation: BMC Proceedings 2010 4(Suppl 2):P51

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The effect of cisplatin in 5637 bladder cancer cell line

Authors: Rosário Pinto-Leite, Regina Arantes-Rodrigues, M Luís Cardoso, Lúcio Santos and Paula A Oliveira

Citation: BMC Proceedings 2010 4(Suppl 2):P52

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Identification of copy number variations of chromosomes 7, 9 and 10 in human glioblastomas by SNP-arrays

Authors: Inês Crespo, Maria D Tabernero, Ana B Nieto, Olinda Rebelo, Hermínio Tão, Fernando Gomes, Catarina R Oliveira, Maria C Lopes and Alberto Orfao

Citation: BMC Proceedings 2010 4(Suppl 2):P53

Content type: Poster presentation Published on: 24 September 2010
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Circadian gene variants and MT6s level in nurses under different work shifts – preliminary results

Authors: Edyta Reszka, Beata Peplonska, Edyta Wieczorek, Jolanta Gromadzinska, Wojciech Sobala, Wojciech Wasowicz, Agnieszka Bukowska and Jenny A Lie

Citation: BMC Proceedings 2010 4(Suppl 2):P54

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MFSD2A is a novel lung tumour suppressor gene whose expression is modulated by a 5’-region polymorphism

Authors: Francesca Colombo, Monica Spinola, Felicia S Falvella, James P Sullivan, David S Shames, Luc Girard, Paola Spessotto, John D Minna and Tommaso A Dragani

Citation: BMC Proceedings 2010 4(Suppl 2):P55

Content type: Poster presentation Published on: 24 September 2010
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FGFR4 GLY388ARG polymorphism modulates cancer patients' survival in pooled analysis

Authors: Elisa Frullanti and Tommaso A Dragani

Citation: BMC Proceedings 2010 4(Suppl 2):P56

Content type: Poster presentation Published on: 24 September 2010
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KRAS and EGFR mutations coexisting in lung adenocarcinoma

Authors: Vitor Sousa, Ana Alarcão, Patricia Couceiro, Maria R Silva, Maria J d’Aguiar, Lia Teixeira and Lina Carvalho

Citation: BMC Proceedings 2010 4(Suppl 2):P57

Content type: Poster presentation Published on: 24 September 2010
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Modulation of DNA damage prevention and signaling pathways in diet induced colon cancer prevention

Authors: Dalila FN Pedro, Alice A Ramos, Cristóvão F Lima, Fátima Baltazar and Cristina Pereira-Wilson

Citation: BMC Proceedings 2010 4(Suppl 2):P58

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miR-143 over-expression reduces the growth of xenograft tumors from colon carcinoma cells

Authors: Pedro M Borralho, Sofia Gomes, Raquel T Lima, Rui E Castro, Maria H Vasconcelos and Cecília MP Rodrigues

Citation: BMC Proceedings 2010 4(Suppl 2):P59

Content type: Poster presentation Published on: 24 September 2010
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Histone deacetylation - a new epigenetic target in cancer

Authors: João A Carvalho, Emília Cortesão, José D Branco, Ana C Gonçalves, Sílvia Neves, Filipa Carvalho, André Ribeiro, Vera Alves, Teresa Silva, Marília Dourado, José M Nascimento-Costa and Ana B Sarmento-Ribeiro

Citation: BMC Proceedings 2010 4(Suppl 2):P60

Content type: Poster presentation Published on: 24 September 2010
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EGFR unusual mutation status in lung adenocarcinomas

Authors: Ana Alarcão, Vitor Sousa, Patrícia Couceiro, Maria Silva, Maria J d’Aguiar, Lia Teixeira and Lina Carvalho

Citation: BMC Proceedings 2010 4(Suppl 2):P61

Content type: Poster presentation Published on: 24 September 2010
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Identification of a common deletion region in 10q26 associated with human gliomas

Authors: Margarida Alves, Paulo Liberato, Ana Rita Conde, Manuela Mafra, Alexandra Inverno, Ana Teresa Maia, Denise Bagrel, Isabel Carreira, Miguel Brito and Carolino Monteiro

Citation: BMC Proceedings 2010 4(Suppl 2):P62

Content type: Poster presentation Published on: 24 September 2010
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STEAP1 expression in prostate cancer and its regulation by androgens

Authors: Inês Gomes, Cecília RA Santos, Sílvia Socorro, Carlos Lopes and Cláudio J Maia

Citation: BMC Proceedings 2010 4(Suppl 2):P63

Content type: Poster presentation Published on: 24 September 2010
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EGFR/erb-1, HER2/erb-2, CK7, LP34, Ki67 and p53 expression in preneoplastic lesions of bronchial epithelium

Authors: Lina Carvalho, Joana E Santo, Ana Alarcão, Patricia Couceiro, Maria R Silva, Ana Gomes, Maria J d’Aguiar, Lia Teixeira and Vitor Sousa

Citation: BMC Proceedings 2010 4(Suppl 2):P64

Content type: Poster presentation Published on: 24 September 2010
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Improving the classification of brain tumors in mice with perturbation enhanced (PE)-MRSI

Authors: Rui V Simões, Sandra Ortega-Martorell, Teresa Delgado-Goñi, Yann le Fur, Marti Pumarola, Ana P Candiota, Patrick J Cozzone, Margarida Juliá-Sapè and Carles Arús

Citation: BMC Proceedings 2010 4(Suppl 2):P65

Content type: Poster presentation Published on: 24 September 2010
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NMR metabonomic study of lung cancer: metabolic profiling of tissues

Authors: Cláudia M Rocha, António S Barros, Ana M Gil, Brian J Goodfellow, Isabel M Carreira, João Bernardo, Ana Gomes, Vítor Sousa, Lina Carvalho and Iola F Duarte

Citation: BMC Proceedings 2010 4(Suppl 2):P66

Content type: Poster presentation Published on: 24 September 2010
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NMR metabonomic study of lung cancer: metabolic profiling of urine and blood plasma

Authors: Joana Carrola, Cláudia M Rocha, António S Barros, Ana M Gil, Brian J Goodfellow, Isabel M Carreira, João Bernardo, Ana Gomes, Vitor Sousa, Lina Carvalho and Iola F Duarte

Citation: BMC Proceedings 2010 4(Suppl 2):P67

Content type: Poster presentation Published on: 24 September 2010
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Abstracts of the 16th International Charles Heidelberger Symposium on Cancer Research

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