Table 2 Bayesian-network-based risk prediction performance using SNPs of different functional annotations
Type of SNP used to construct the Bayesian network | Mean AUC value using only genes | Mean AUC value using genes and environmental variables | Mean AUC value using gene and environment variables and quantitative traits |
|---|---|---|---|
Nonsynonymous only | 0.61 ± 0.02 | 0.83 ± 0.02 | 0.96 ± 0.01 |
Synonymous only | 0.52 ± 0.02 | 0.79 ± 0.02 | 0.95 ± 0.01 |