Figure 1
From: Mining the TRAF6/p62 interactome for a selective ubiquitination motif
Model illustrating the interaction between the ligase and scaffold in directing substrate ubiquitination. A: Schematic representation of the means by which the E3 ligase, TRAF6, interacts with the scaffold, p62, and selects a specific Lysine for ubiquitination. B: The sequence of the consensus motif identified in TRAF6/p62 substrates.